The band was set up on 2nd March 1953 as a bugle, fife and drum band. It was only in 1957 that the band was converted into Singapore's first school military band. Subsequently, the band slowly evolved into a concert band in the mid-1980s. Over the years, the Saint Patrick’s School Military Band has established itself as one of the most outstanding secondary school bands in Singapore under the baton of their bandmaster, Mr David Glosz since his arrival in 1984. With the sustained records of achievements over the years, the Ministry of Education (MOE) has recognized and awarded the school band as a Niche Programme School in 2007. 

Their achievements started from being the first school band from Asia to participate at the St. Patrick’s Day parade in New York in 1982, to their continued success at the Singapore Youth Festival Central Judging in 1990, 1992, 1995, 1997, 1999, 2001 and 2003. In 2005, 2007, 2009 and 2011, the band advanced into Gold with Honours band, adding to their achievements of an unprecedented eleven consecutive Gold awards. At the 2013 Singapore Youth Festival Arts Presentation, the school band managed to maintain their excellence in music by achieving yet another top award of Certificate of Distinction. In 1991, the band has had the honour of being commended under “The achievement of Excellence” in the Ministry of Information and The Arts publication of Singapore. In 2004 and 2005, the band participated in the “Balloon Hat Festival”, an event organised by Sentosa and the Ministry of Education Co-Curricular Activities Branch and was awarded third in the “Vote For Your Favourite Band Contest” and first in the “People’s Choice Award”. 

The band has also performed on many occasions at the Band Fiesta and was proud to receive the “Grooviest In the Gardens Award” in “Shell-MOE School Band Fiesta In the Gardens 2005”. They have also performed for the President & Prime Minister of Singapore at various state functions at the Istana. Not only has the band achieved distinctions locally, it has also achieved Gold Awards at overseas music festivals such as the Western Australia Band Associations Festival (1991), Australia International Music Festival (2010) and the Pacific Basin Music Festival (1993, 2000 & 2006) which was held in Honolulu, Hawaii. It was also the first Singapore band to undertake a goodwill tour to the United States of America and be awarded distinctions at a foreign music festival. 

Touring around the world, the band has been to places such as the United States of America (Los Angeles , San Francisco, New York, Chicago and Washington D.C. 1982), Perth, Australia (1989, 1991, 1995, 2002, 2008 and 2010), Sarawak, Malaysia (1991), Kuala Lumpur, Malaysia, (2007, 2009, 2011), Auckland, New Zealand (1999) and Honolulu, Hawaii (1993 and 2000). In 2004, the band was nominated by the Queensland Conservatorium, Griffith University to participate in the Southern Cross International Music Festival in Brisbane, Australia. In 2006, the band set off to Honolulu, Hawaii for about 2 weeks to gain more musical and cultural exposure and experiences with their participation in the 21st Annual Pacific Basin Music Festival 2006 and was awarded two Gold Awards and Command Performance. On 26th June 2010, the band set off to Sydney, Australia for about a week to participate in the 21st Annual Australian International Music Festival and was awarded a Gold award and Command Performance. The band also had their most recently music and cultural exchange at  Gold Coast, Australia in 2014.

Locally, the band held their very first public concert entitled Variations I in 1989. Since then, it has organised several public concerts namely: Variations II (1991), Alpha and Omega (1992), Variations III (1993), Crown Imperial (1995), Variations (1998), Military Band in Concert (2000), A Musical Heritage (2001), Patricians Night (2003), St. Patrick’s School Military Band in Concert (2004), A Celebration of a Patrician’s Life (2005), Patricians Go POP (2006), Potest Qui Vult (2008), Of Pride and Celebration (2010) and the most recent, Night of Music To Remember (2011).

The band organised its most recent concert in 2014 at the Esplanade Concert Hall in February. It was entitled "A Musical Homecoming", in celebration of the school's band's 60th Anniversary. The concert showcased a myriad of musical pieces performed by the band as well as the alumni and some of the younger brothers' of the Lasallian family (St. Stephen's School, St. Anthony's Primary School, St. Joseph's Institution Junior). In addition, the band had the privilege to perform to a few of the band's pioneer members at this concert. Several other band alumni throughout the ages, together with their fellow school mates attended this memorable concert too. To have seen their proud faces after witnessing how much the band has achieved over the decades was a truly sight to behold. It was undoubtedly a once in a lifetime performance on a very special evening.